Some of the changes in the upgrade from WordPress 2.2 to 2 .51, seem to have been damaging to the interface experience when editing, the save and publish buttons are no longer as clear in this version nor as easy to locate on-screen By being placed on the right-hand side, rather than under the post as before, also the tabs at the top of the screen and their subheadings are a bit wishy-washy, the interface seems to suffer generally from a busy vagueness. I personally think post category was much better on the right-hand side of the write post interface, and save should be directly below the post that you are writing.
I will get used to these changes, but most of them smelt of unnecessary fiddling.